Drug eruption - Letusan Ubar
☆ Dina hasil Stiftung Warentest 2022 ti Jerman, kapuasan konsumen sareng ModelDerm ngan ukur langkung handap tibatan konsultasi telemedicine anu mayar.
Letusan Ubar (Drug eruption) dicirikeun ku mangaruhan sakabéh awak.
References
Réaksi kulit disababkeun ku nginum obat, katelah bitu ubar, kadang bisa jadi parna. Réaksi parna ieu, disebut severe cutaneous adverse drug reactions (SCARs) , dianggap ngancam kahirupan. Éta kalebet kaayaan sapertos Stevens-Johnson syndrome (SJS) , toxic epidermal necrolysis (TEN) , acute generalized exanthematous pustulosis (AGEP) , and drug reaction with eosinophilia and systemic symptoms (DRESS) . Sanaos SCARs jarang, sakitar 2% pasien dirawat di rumah sakit ngalaman aranjeunna.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Adverse drug reactions involving the skin are commonly known as drug eruptions. Severe drug eruption may cause severe cutaneous adverse drug reactions (SCARs), which are considered to be fatal and life-threatening, including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP), and drug reaction with eosinophilia and systemic symptoms (DRESS). Although cases are relatively rare, approximately 2% of hospitalized patients are affected by SCARs.
Wanoja umur 31 taun nganjang ka departemen dermatologi kalayan bintik beureum henteu aya rasa nyeri dina luhureun suku katuhuna. Anjeunna nyandak hiji dosis doxycycline (100 mg) dinten sateuacanna, saatos perlakuan laser picosecond pikeun parut jarawat. Taun ka tukang, anjeunna ngalaman masalah anu sami di tempat anu sami saatos nyandak dosis doxycycline post-laser anu sami. Anjeunna henteu ngagaduhan riwayat médis anu signifikan sareng henteu aya gejala sanés, sapertos muriang, sacara lokal atanapi sapanjang awakna.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
A 31-year-old woman presented to the dermatology department with an asymptomatic erythematous patch on the dorsum of her right foot. She had taken 1 dose of doxycycline (100 mg) the previous day as empirical treatment after picosecond laser treatment for acne scars. She had had a similar episode the previous year on the same site, after taking the same dose of doxycycline after laser treatment. She had no notable medical history, and no other local or systemic symptoms, including fever.
Stevens-Johnson syndrome (SJS) sareng toxic epidermal necrolysis (TEN) mangrupikeun dua bentuk réaksi kulit anu serius, béda sareng kaayaan kulit sanés sapertos erythema multiforme major sareng sindrom kulit scalded staphylococcal, ogé réaksi narkoba. SJS/TEN mangrupa réaksi langka tur parna ngabalukarkeun karuksakan kulit jeung mémbran mukosa nyebar, mindeng kalawan gejala sistemik. Dina langkung ti 80% kasus, pangobatan mangrupikeun panyababna.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) are variants of the same condition and are distinct from erythema multiforme major staphylococcal scalded skin syndrome, and other drug eruptions. Stevens-Johnson syndrome/toxic epidermal necrolysis is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss accompanied by systemic symptoms. Medications are causative in over 80% of cases.
Erupsi ubar didiagnosis utamana tina sajarah médis sareng pamariksaan klinis. Biopsi kulit, tés getih atanapi tés imunologis ogé tiasa mangpaat.
Conto ubar umum anu nyababkeun letusan nyaéta antibiotik sareng obat antimikroba sanés, obat sulfa, obat anti radang nonsteroid (NSAID), agén kémoterapi pikeun malignancies, antikonvulsan sareng obat psikotropika.
○ Diagnosis sareng Perawatan
Upami Anjeun gaduh muriang (naékna suhu awak), Anjeun kudu neangan perhatian médis pas mungkin. Ubar anu disangka kedah dileungitkeun (sapertos antibiotik, obat anti radang non-stéroid). Sateuacan nganjang ka rumah sakit, antihistamin lisan sapertos cetirizine atanapi loratadine tiasa ngabantosan gatal sareng ruam.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]
Tes getih (CBC, LFT, jumlah eosinofil)
Stéroid lisan sareng antihistamin kalayan resép dokter